PKR 000,000

ROLE OF MEDICATION

Description
When diet and exercise alone is not sufficient to control blood glucose level, then doctors advise the use of medication depending on:

type of diabetes
blood glucose level
duration of diabetes
presence or absence of complications of diabetes
INSULIN: Insulin is the hormone produced in our body by the pancreas that helps in proper utilization of glucose. In type 1 diabetes, pancreas fails to produce insulin completely, so the required insulin has to be injected. Whereas in type 2 diabetes, pancreas is producing some insulin but this insulin is not effective so there are medicines that will help this insulin to work better. Initially animal insulins were used, derived from beef or pork, they caused allergic reactions. Nowadays only genetically engineered human and synthetic insulins are used that have literally no side effects. Insulin cannot be taken as a pill as it will be destroyed by enzymes in our stomach so it has to be injected in the fat under the skin from where it is gradually released.

Types of Insulin: Depending on onset, and duration of action there are following types of insulin

Rapid acting Starts acting in 5-10 min, reaches peak action in 1 hour and total duration of action is up to 2 hours These include lispro, aspart and glulisine insulin

Short acting Action starts in 25-30 min after injection, reaches peak action in 2 hours, complete duration of action is around 5-6 hours This type includes Regular human insulin

Intermediate acting Action starts in 2-4 hours , peak action at 4-12 hours, duration of action 12- 18 hours NPH insulin is an example of intermediate acting insulin

Long acting Ultra lente starts to work in 6-10 hours and has a duration of action lasting 20-24 hours Glargine and detemir have a total duration around 20-24 hours, they have no peak of action, they maintain a basal level of insulin in the blood at all times.
Posted
Aug 24, 2019
Location
Country
Pakistan
Province
Punjab
City
Lahore
Address
71-A, Jail Road, Near Apwa College Lahore, Pakistan
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